The symptoms of mesothelioma typically arise 20 to 50 years after initial exposure to asbestos occurs. The commonality of the symptoms, which, in the case of pleural mesothelioma, often resemble less-serious conditions such as influenza, can make mesothelioma very difficult to diagnose. Symptoms include:

-Shortness of breath
-Chest pain
-Persistent coughing
-Fatigue
-Night sweats or fever
-Unexplained weight loss